Structural Basis for Reduced Staphylocoagulase-mediated Bovine Prothrombin Activation
نویسندگان
چکیده
منابع مشابه
Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions.
Staphylocoagulase (SC) is a potent nonproteolytic prothrombin (ProT) activator and the prototype of a newly established zymogen activator and adhesion protein family. The staphylocoagulase fragment containing residues 1-325 (SC-(1-325)) represents a new type of nonproteolytic activator with a unique fold consisting of two three-helix bundle domains. The N-terminal, domain 1 of SC (D1, residues ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2006
ISSN: 0021-9258
DOI: 10.1074/jbc.m507957200